Dynamic signaling for neural stem cell fate determination
نویسندگان
چکیده
منابع مشابه
Signaling pathways governing stem-cell fate.
Hematopoietic stem cells (HSCs) are historically the most thoroughly characterized type of adult stem cell, and the hematopoietic system has served as a principal model structure of stem-cell biology for several decades. However, paradoxically, although HSCs can be defined by function and even purified to near-homogeneity, the intricate molecular machinery and the signaling mechanisms regulatin...
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Extracellular matrix (ECM) and growth factor signaling networks are known to interact in a complex manner. Therefore, reductionist approaches that test the cellular response to individual ECM components and growth factors cannot be used to predict the response to more complex mixtures without knowledge of the underlying signaling network. To address this challenge, we have developed a technolog...
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ژورنال
عنوان ژورنال: Cell Adhesion & Migration
سال: 2009
ISSN: 1933-6918,1933-6926
DOI: 10.4161/cam.3.1.7602